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ISSN: 0860-7796
BioTechnologia
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2/2024
vol. 105
 
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abstract:
REVIEW PAPER

Genetics of antibiotic resistance in methicillin-resistant Staphylococcus aureus (MRSA)

Klementyna Marciniak
1
,
Agata Tyczewska
1
,
Kamilla Grzywacz
1

  1. Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznań, Poland
BioTechnologia vol. 105(2) ∙ pp. 169–177 ∙ 2024
DOI: https://doi.org/10.5114/bta.2024.139756
Online publish date: 2024/06/25
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Methicillin-resistant Staphylococcus aureus (MRSA) strains pose a significant threat as common causes of bac­terial infections in hospitals, often resistant to available antibiotics such as daptomycin, vancomycin, and linezolid. The continuous emergence of new MRSA isolates with no effective treatment options underscores a real threat to health among humans and animals, and the number of effective antibiotic therapies decreases with each pas­sing year. In this review, we provide an overview of the most common genetic mechanisms of resistance to a broad spectrum of antibiotics in methicillin-resistant S. aureus.
keywords:

Staphylococcus aureus, MRSA, antibiotic resistance


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