eISSN: 2391-6052
ISSN: 2353-3854
Alergologia Polska - Polish Journal of Allergology
Current issue Archive Manuscripts accepted About the journal Supplements Special issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
1/2018
vol. 5
 
Share:
Share:
abstract:
Guidelines/recommendations

Hypersensitivity to iodine contrast media. Guidelines of the Section of Drug Hypersensitivity of the Polish Society of Allergology

Marita Nittner-Marszalska
,
Grażyna Bochenek
,
Anna Bodzenta-Łukaszyk
,
Joanna Glück
,
Marek L. Kowalski
,
Grzegorz Porębski
,
Barbara Rymarczyk
,
Grażyna Sławeta
,
Joanna Makowska

Alergologia Polska – Polish Journal of Allergology 2018; 5, 1: 51–57
Online publish date: 2018/03/23
View full text Get citation
 
PlumX metrics:
Iodinated contrast agents (ICAs) are broadly used in radiology. Frequency of adverse events, including hyperreactivity reactions, noted after their application grows in correlation with the steady increase in the numbers of radio-diagnostic tests performed. Hyperreactivity reactions occur most frequently with the use of ionic ICAs; much rarer with non-ionic ones. Clinical manifestations of hyperreactivity reactions to ICAs involve two groups of symptomatologically typical reactions: immediate and non-immediate (occurring < 60 minutes and > 60 minutes after ICAs’ application). The main risk factors of the occurrence and severity of these reactions are: the previous history of such reactions, poorly controlled asthma, and clonal mast cell activation diseases. Diagnosis of sensitivity to ICAs shares the same procedures and tests used in diagnosing other allergies. The more time passes since the manifestation of sensitivity, the less reliable the diagnostic test is. The predictive value of both positive and negative diagnostic results is limited. In patients with a history of sensitivity reactions to ICAs, before any subsequent radiological test, premedication (antihistamine drugs and steroids) is recommended. This, however, does not guarantee full security, especially in patients with a history of anaphylaxis following the use of ICAs.
keywords:

iodinated contrast agents, low-ionic contrast agents, hypersensitivity to iodinated contrast agents, premedication in allergy to iodinated contrast agents



Quick links
© 2024 Termedia Sp. z o.o.
Developed by Bentus.