eISSN: 2084-9885
ISSN: 1896-6764
Neuropsychiatria i Neuropsychologia/Neuropsychiatry and Neuropsychology
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1-2/2024
vol. 19
 
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abstract:
Original article

Prevalence of alcohol abuse in patients with rheumatic diseases participating in a clinical trial

Ewa Mojs
1
,
Marta Jeka
2
,
Marzena Waszczak-Jeka
3
,
Bogusław Stelcer
1
,
Natalia Trzeszczynska
1
,
Dorota Sikorska
1
,
Włodzimierz Samborski
1

  1. Poznan University of Medical Sciences, Poznań, Poland
  2. MICS Medical Centre, Warsaw, Poland
  3. Nasz Lekarz Przychodnie Medyczne, Toruń, Poland
Neuropsychiatria i Neuropsychologia 2024; 19, 1–2: 9–16
DOI: https://doi.org/10.5114/nan.2024.141885
Online publish date: 2024/08/12
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Introduction:
Phenomena such as a pandemic can cause many medical, psychological, and sociological problems, including increased alcohol use, which was noticed among healthy people and patients with long-term diseases. The aim of the study was to evaluate alcohol consumption in adult patients with rheumatic diseases, who completed participation in a phase 3 clinical trial for biologic drugs or treatment under a drug program, and consented to participate in the study.

Material and methods:
128 patients between the ages of 18 and 77 years (M = 46.88, SD = 13.80) with disease duration of 1-46 years (M = 12.30, SD = 8.53) participated in the study. In the research group, more than half (57.8%) were women, most of the subjects (60.2%) were economically active, 74.2% of the subjects are not addicted to tobacco, 61.7% of the subjects were in a relationship, 52.3% of the patients were participating in a drug program at the time of the study, and 23.4% of the subjects had completed participation in clinical trials. The Baltimore questionnaire and AUDIT-4 were used in the study.

Results:
Regarding the norms set by the authors of the Baltimore test, it was recognised that 24 people (18.8%) had an alcohol problem, medium risk of disease applied to 6 people (4.7%), low risk of disease applied to 12 people (9.4%), and no alcohol problem applied to 86 people (67.2%).

Conclusions:
Alcohol drinking is a serious problem among patients treated in drug programs and clinical trials. Smoking is significantly associated with alcohol abuse and drinking patterns. It is necessary to control with alcohol drinking questionnaires during treatment with expensive drugs, to identify alcohol abuse or risky drinking patterns as a factor that may reduce compliance.

keywords:

alcohol use, addiction, clinical trials, long term diseases, rheumatic diseases
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