eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Reviewers Abstracting and indexing Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
1/2013
vol. 10
 
Share:
Share:
abstract:

THORACIC SURGERY
Results of the surgical treatment of patients suffering from bronchopulmonary carcinoid tumors in the Department of Thoracic Surgery in Bystra in the period 1990-2011

Alina J. Wiencek-Weiss
,
Piotr Wandzel
,
Paweł B. Rogoziński
,
Tomasz Kaczor
,
Józef Ryszka
,
Witold Brózda
,
Adam Bubel
,
Krzysztof Bruliński

Kardiochirurgia i Torakochirurgia Polska 2013; 10 (1): 34–41
Online publish date: 2013/04/05
View full text Get citation
 
PlumX metrics:
Background: The new classification and terminology concerning neuroendocrine tumors, according to the European Neuroendocrine Tumor Society (ENETS) guidelines, were not universally accepted for bronchopulmonary carcinoids. That is why the term “carcinoid” is still being used in its traditional meaning. Precise identification of bronchopulmonary carcinoid subtypes constitutes an important prognostic factor.

Aim of the study: The aim of the study was to present the results of bronchopulmonary carcinoid surgical treatment conducted at the Department of Thoracic Surgery in Bystra, to assess the surgery material in accordance with the WHO 1999 (Travis) classification, and to compare the clinical courses of typical and atypical carcinoid tumors.

Material and methods: The analysis included 159 patients aged 18-77, treated surgically due to bronchopulmonary carcinoids in the years 1990-2011. Reassessment of histological preparations was carried out according to the WHO 1999 (Travis) and International Association for the Study of Lung Cancer (IASLC) classification; check-ups of the treated patients were performed as well. Disease-free interval (DFI) and overall survival were assessed with the Kaplan-Meier method; the clinical course of typical and atypical carcinoids was compared.

Results: As a result of the histological reassessment, 142 patients (88.3%) were diagnosed with typical carcinoids, and 17 patients (11.7%) with atypical carcinoids. During the follow-up period, local disease recurrence occurred in 8 (4.9%) patients, distant metastases in 13 (8.2%) patients. There were 26 (16.4%) instances of death – 2 because of other malignant neoplasms. The DFI median (p = 0.00003) and overall survival (p < 0.00001) were significantly longer in patients with typical carcinoids than in patients with atypical types of the tumor.

Conclusions: The histological subtype of a bronchopulmonary carcinoid tumor is the dominant prognostic factor in assessing the DFI and the 5-year survival after surgery.
keywords:

typical carcinoid, atypical carcinoid, neuroendocrine tumors

Quick links
© 2024 Termedia Sp. z o.o.
Developed by Bentus.