Adaptive optics imaging in the most common inherited retinal degenerations

Katarzyna Samelska; Magdalena Kupis; Anna Zaleska-Żmijewska; Jacek P. Szaflik

doi:10.5114/ko.2021.107769

POLSKI

eISSN: 2719-3209
ISSN: 0023-2157

Klinika Oczna / Acta Ophthalmologica Polonica

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2/2021
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abstract:

Review paper

Adaptive optics imaging in the most common inherited retinal degenerations

Katarzyna Samelska

^{1, 2}

,

Magdalena Kupis

^{1, 2}

,

Anna Zaleska-Żmijewska

^{1, 2}

,

Jacek P. Szaflik

^{1, 2}

Department of Ophthalmology, Medical University of Warsaw, Poland
SPKSO Ophthalmic University Hospital, Warsaw, Poland

KLINIKA OCZNA 2021, 123, 2:74–79

DOI: https://doi.org/10.5114/ko.2021.107769

Online publish date: 2021/07/14

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Adaptive optics is the imaging technique of the retina. It finds use in visualizing microscopic changes in the retinal photoreceptors and the retinal blood vessels. Introducing adaptive optics as a diagnostic tool facilitated diagnosing inherited retinal diseases, such as Stargardt disease, cone-rod dystrophy, and retinitis pigmentosa. These diseases are often inherited in a heterogenous pattern. Thus, genetic testing often fails to give a certain diagnosis. Optical coherence tomography, fundus autofluorescence, fluorescein angiography, visual field examination and electrophysiological testing are vital for diagnosing patients with inherited retinal diseases. Adaptive optics imaging complements diagnosing and monitoring conditions such as Stargardt disease and cone-rod dystrophy. In this article we sum up the main characteristics of inherited retinal diseases in adaptive optics imaging.

keywords:

Adaptive optics imaging in the most common inherited retinal degenerations

Katarzyna Samelska 1, 2 , Magdalena Kupis 1, 2 , Anna Zaleska-Żmijewska 1, 2 , Jacek P. Szaflik 1, 2

adaptive optics, Stargardt disease, cone-rod dystrophy, retinitis pigmentosa

Katarzyna Samelska

^{1, 2}

,

Magdalena Kupis

^{1, 2}

,

Anna Zaleska-Żmijewska

^{1, 2}

,

Jacek P. Szaflik

^{1, 2}