Comparison of efficacy and safety of postoperative treatment with loteprednol etabonate and bromfenac after phacoemulsification

Magdalena Kucharczyk-Pośpiech; Piotr Jurowski; Wiktoria Kubisiak; Monika Chwiałkowska-Karam; Michał Wilczyński; Sylwia Konarska; Wojciech Omulecki

doi:10.5114/ko.2019.84564

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ISSN: 0023-2157

Klinika Oczna / Acta Ophthalmologica Polonica

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1/2019
vol. 121

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abstract:

Original paper

Comparison of efficacy and safety of postoperative treatment with loteprednol etabonate and bromfenac after phacoemulsification

Magdalena Kucharczyk-Pośpiech

¹

,

Piotr Jurowski

²

,

Wiktoria Kubisiak

²

,

Monika Chwiałkowska-Karam

²

,

Michał Wilczyński

¹

,

Sylwia Konarska

¹

,

Wojciech Omulecki

¹

Department of Ophthalmology, Norbert Barlicki Memorial Teaching Hospital No. 1, Medical University of Lodz, Poland Head: Professor Wojciech Omulecki MD, PhD
Department of Ophthalmology and Visual Rehabilitation, Central Veterans Hospital, Medical University of Lodz, Poland Head: Professor Piotr Jurowski MD, PhD

DOI: https://doi.org/10.5114/ko.2019.84564

Online publish date: 2019/06/05

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AMA

Kucharczyk-Pośpiech M, Jurowski P, Kubisiak W, et al. Comparison of efficacy and safety of postoperative treatment with loteprednol etabonate and bromfenac after phacoemulsification. Klinika Oczna / Acta Ophthalmologica Polonica. 2019;121(1):18-22. doi:10.5114/ko.2019.84564.

APA

Kucharczyk-Pośpiech, M., Jurowski, P., Kubisiak, W., Chwiałkowska-Karam, M., Wilczyński, M.,  & Konarska, S. et al. (2019). Comparison of efficacy and safety of postoperative treatment with loteprednol etabonate and bromfenac after phacoemulsification. Klinika Oczna / Acta Ophthalmologica Polonica, 121(1), 18-22. https://doi.org/10.5114/ko.2019.84564

Chicago

Kucharczyk-Pośpiech, Magdalena, Piotr Jurowski, Wiktoria Kubisiak, Monika Chwiałkowska-Karam, Michał Wilczyński, Sylwia Konarska,  and Wojciech Omulecki. 2019. "Comparison of efficacy and safety of postoperative treatment with loteprednol etabonate and bromfenac after phacoemulsification". Klinika Oczna / Acta Ophthalmologica Polonica 121 (1): 18-22. doi:10.5114/ko.2019.84564.

Harvard

Kucharczyk-Pośpiech, M., Jurowski, P., Kubisiak, W., Chwiałkowska-Karam, M., Wilczyński, M., Konarska, S.,  and Omulecki, W. (2019). Comparison of efficacy and safety of postoperative treatment with loteprednol etabonate and bromfenac after phacoemulsification. Klinika Oczna / Acta Ophthalmologica Polonica, 121(1), pp.18-22. https://doi.org/10.5114/ko.2019.84564

MLA

Kucharczyk-Pośpiech, Magdalena et al. "Comparison of efficacy and safety of postoperative treatment with loteprednol etabonate and bromfenac after phacoemulsification." Klinika Oczna / Acta Ophthalmologica Polonica, vol. 121, no. 1, 2019, pp. 18-22. doi:10.5114/ko.2019.84564.

Vancouver

Kucharczyk-Pośpiech M, Jurowski P, Kubisiak W, Chwiałkowska-Karam M, Wilczyński M, Konarska S et al. Comparison of efficacy and safety of postoperative treatment with loteprednol etabonate and bromfenac after phacoemulsification. Klinika Oczna / Acta Ophthalmologica Polonica. 2019;121(1):18-22. doi:10.5114/ko.2019.84564.

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Aim
Comparison of efficacy and safety of loteprednol etabonate and bromfenac after phacoemulsification.

Material and methods
Multicenter prospective case series. Consecutive 58 patients (58 eyes) were randomly assigned to the one of the study groups regarding postoperative treatment. Patients in Group I used 0.09% bromfenac 2 times diurnally for 30 days, and patients in Group II used 0.5% loteprednol etabonate 4 times diurnally for 30 days. The laser flare-cell photometry, slit lamp examination, tonometry and optical coherence tomography of macula were performed preoperatively and postoperatively at 1, 7, 30 and 90 days.

Results
The distance best corrected visual acuity was 0. 93 in group I and 0.91 in w group II. Laser Flare Photometry, central macular thickness and intraocular pressure was not significantly different during the 3 months of treatment between the groups (p> 0.05). In both groups, there were no abnormalities in routine slit lamp examination of the anterior and posterior segment.

Conclusions
The results of the study suggest that topical bromfenac and topical loteprednol etabonate had similar effect on laser flare-cell photometry and foveal thickness in the postoperative period after uneventful phacoemulsification.

keywords:

Comparison of efficacy and safety of postoperative treatment with loteprednol etabonate and bromfenac after phacoemulsification

Magdalena Kucharczyk-Pośpiech 1 , Piotr Jurowski 2 , Wiktoria Kubisiak 2 , Monika Chwiałkowska-Karam 2 , Michał Wilczyński 1 , Sylwia Konarska 1 , Wojciech Omulecki 1

loteprednol etabonate, bromfenac, phacoemulsification, cataract, steroids, NSAID

Magdalena Kucharczyk-Pośpiech

¹

,

Piotr Jurowski

²

,

Wiktoria Kubisiak

²

,

Monika Chwiałkowska-Karam

²

,

Michał Wilczyński

¹

,

Sylwia Konarska

¹

,

Wojciech Omulecki

¹