|
Current issue
Archive
Videos
Articles in press
About the journal
Supplements
Editorial board
Reviewers
Abstracting and indexing
Subscription
Contact
Instructions for authors
Publication charge
Ethical standards and procedures
Editorial System
Submit your Manuscript
|
4/2010
vol. 112 abstract:
Original paper
Concentration assessment of interleukin 8 in serum at children with uveitis
Beata Żelazowska-Rutkowska
1
,
Małgorzata Mrugacz
2
,
Jolanta Wysocka
1
,
Alina Bakunowicz-Łazarczyk
2
Online publish date: 2010/12/22
View
full text
Get citation
ENW EndNote
BIB JabRef, Mendeley
RIS Papers, Reference Manager, RefWorks, Zotero
AMA
APA
Chicago
Harvard
MLA
Vancouver
Purpose: Uveitis in children is a visual threatening disease with a complication rate of more than 75%. At the children the
uveitis differs in several aspect from adults like: clinical presentation or complication of disease. The etiology of uveitis is still unknown, but T lymphocytes are generally key mediators of the pathogenesis of uveitis. In our study we evaluate IL-8 concentration in serum in uveitis patients. Material and methods: Serum sample were collected from 28 uveitis patients and 20 people from control group. The level of IL-8 was measured with specific enzyme- linked immunoassays ELISA methods (R & D Systems). Results: Level of IL-8 in uveitis group was a significant higher (p<0.04) compared with control group. Conclusions: Increased levels of interleukin 8 in serum of children with uveitis may suggest innate immune mechanisms in the acute disease. |
|
POLSKI
