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eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
Bieżący numer Archiwum Filmy Artykuły w druku O czasopiśmie Suplementy Rada naukowa Recenzenci Bazy indeksacyjne Prenumerata Kontakt Zasady publikacji prac Opłaty publikacyjne Standardy etyczne i procedury
Panel Redakcyjny
Zgłaszanie i recenzowanie prac online
SCImago Journal & Country Rank
1/2025
vol. 127
 
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Opis przypadku

Zoledronate-induced orbital and ocular inflammation

Julia Dyrda
1
,
Karolina Starkowska
1

  1. Department of Ophthalmology, Józef Struś Multi-Speciality Municipal Hospital in Poznan, Poland
KLINIKA OCZNA 2025, 127, 1: 34-36
Data publikacji online: 2025/03/25
Metryki PlumX:


Orbital inflammation is one of numerous adverse effects of bisphosphonates. The symptoms include palpebral oedema, conjunctival chemosis, ocular motility impairment, proptosis and decreased visual acuity. This condition may coincide with other ocular adverse effects, as presented in this case report of a patient who developed orbital inflammation along with scleritis and uveitis after the administration of zoledronic acid for bone metastases of prostate cancer. He was admitted to the hospital with severely decreased visual acuity (hand motion) and massive oedema and proptosis. Following the execution of diagnostic imaging, intravenous steroids (methylprednisolone 0.5 g for 3 days) were introduced, leading to rapid alleviation of symptoms. At discharge the patient presented full recovery of visual acuity, which is typical for bisphosphonate ocular adverse effects treated with steroids.
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